Fig. 2.

Qualitative overview of structural variant calling methodology using short reads and long reads and their associated costs. a, A qualitative comparison of the different SV methodologies ranging across technologies (whole genome and RNA-Seq using short and long reads) to different approaches (mapping vs. assembly) with respect to their costs and recall. b, The ratio of improvement in the number of SVs detected from using long reads across four human and two non-human studies. Overall, each study shows a clear improvement of using the longer reads. Additional file 1: Table S1 shows the details of each study