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. 2019 Nov 5;4(21):19238–19245. doi: 10.1021/acsomega.9b02572

Table 3. ANOVA for the Fitted Quadratic Polynomial Model before and after Optimization.

  before optimization
after optimization
source SS df MS F-value P-value SS df MS F-value P-value
model 192.31 9 21.37 110.73 <0.0001 192.00 6 32.00 193.29 <0.0001
A 25.67 1 25.67 133.03 <0.0001 25.67 1 25.67 155.04 <0.0001
B 103.82 1 103.82 538.06 <0.0001 103.82 1 103.82 627.12 <0.0001
C 43.01 1 43.01 222.91 <0.0001 43.01 1 43.01 259.81 <0.0001
AB 6.38 1 6.38 33.04 0.0007 6.38 1 6.38 38.51 0.0001
AC 0.06 1 0.06 0.32 0.5871          
BC 3.40 1 3.40 17.64 0.0040 3.40 1 3.40 20.56 0.0011
A2 0.04 1 0.04 0.20 0.6706          
B2 9.44 1 9.44 48.93 0.0002 9.72 1 9.72 58.69 <0.0001
C2 0.19 1 0.19 1.01 0.3487          
residual 1.35 7 0.19     1.66 10 0.17    
lack of fit 1.35 3 0.45     1.66 6 0.28    
pure error 0.00 4 0.00     0.00 4 0.00    
cor total 193.66 16       193.66 16      
R2 0.9930 0.9915
adj. R2 0.9841 0.9863
pred. R2 0.8884 0.9613
adeq. precision 35.151 45.357