Table 1.
Demographic and clinical characteristics of the study groups
| POMS (n = 16) | AOAMS (n = 23) | AODMS (n = 22) | P‐value | |
|---|---|---|---|---|
| Females, n (%) | 15 (93.8) | 19 (82.6) | 19 (86.4) | 0.94 |
| Age in years, mean (SD) | 38.2 (10.6) | 40 (5) | 52.6 (7.3) | 0.005 |
| Age of onset in years, mean (SD) | 16.7 (1.2) 16 | 34.7 (3.2)a | 27.5 (6.4) | <0.0001 |
| Disease duration in years, mean (SD) | 21.5 (10.3)a | 5.3 (1.6) | 25.1 (3.4) | <0.0001 |
| EDSS, mean (SD) median | 3.2 (2.0) 2.8b | 2.0 (0.9) 2.0 | 3.1 1.8 (2.5) | 0.56 |
| RRMS disease course, n (%) | 16 (100) | 23 (100) | 22 (100) | 0.396 |
MS, multiple sclerosis; PO, pediatric onset; AOA, adult onset age‐matched; AOD; adult onset disease duration‐matched; SD, standard deviation; EDSS, Expanded Disability Status Scale; RR, relapsing‐remitting; n, number; %, percentage. The statistical differences between the three groups were calculated using the chi‐square test, analysis of covariance and Krukal‐Walis test. The statistical differences between the POMS and AOAMS groups were calculated using the chi‐square test, Student's t‐test and Mann‐Whitney test.
a
P < 0.001,
P < 0.01, and
b
P < 0.05 between the POMS and AOAMS groups are reported in relative boxes.