Table 2.
MRI characteristics of the study groups
| Characteristic | POMS (n = 16) | AOAMS (n = 23) | AODMS (n = 22) | P‐value |
|---|---|---|---|---|
| T2‐LV, mean (SD) | 17.9 (17.8) | 10 (9) | 15.7 (14.5) | 0.198 |
| T1‐LV, mean (SD) | 2.7 (5.2) | 2.2 (2.8) | 2.5 (2.8) | 0.930 |
| BPF, mean (SD) | 0.801 (0.03) | 0.827 (0.03) | 0.795 (0.02) | <0.0001 |
| GMF, mean (SD) | 0.410 (0.03) | 0.434 (0.03) | 0.395 (0.02) | <0.0001 |
| WMF, mean (SD) | 0.392 (0.02) | 0.393 (0.02) | 0.397 (0.02) | 0.583 |
MS, multiple sclerosis; PO, pediatric onset; AOA, adult onset age‐matched; AOD; adult onset disease duration matched; SD, standard deviation; BPF, brain parenchymal fraction; GMF, gray matter fraction; WMF, white matter fraction; LV, lesion volume. The lesion volume measures are expressed in milliliters and brain volume measures in fractions. The statistical differences between the groups were calculated using analysis of covariance in which age and disease duration were used as covariates.