Table 3.

Correlations between dentate gyrus (DG) volumetric modifications in multiple sclerosis (MS) patients and clinical, neuropsychological and conventional MRI measures

		Right dentate gyrus		Left dentate gyrus
Group of patients	Variable of interest	No. vertices	r Value (range)	No. vertices	r Value (range)
All MS patients	Disease duration	185	−0.24 (−0.37 to −0.18)	54	−0.21 (−0.29 to −0.18)
	NGMV	162	0.24 (0.18 to 0.37)	146	0.25 (0.18 to 0.34)
	NWMV	40	0.23 (0.18 to 0.31)	27	0.21 (0.18 to 0.25)
RRMS	WL test	–	–	11	0.50 (0.43 to 0.58)
	SS test	–	–	34	0.47 (0.42 to 0.57)
	Brain T2 LV	4	0.42 (0.39 to 0.45)	62	0.43 (0.37 to 0.56)
	Hippocampal T2 LV	79	0.46 (0.38 to 0.60)	34	0.44 (0.38 to 0.54)
SPMS	WL test	52	−0.39 (−0.47 to −0.34)	130	−0.41 (−0.55 to −0.35)
	SS test	–	–	26	−0.38 (−0.44 to −0.34)
	Brain T2 LV	46	0.40 (0.34 to 0.47)	–	–
	Hippocampal T2 LV	26	0.40 (0.34 to 0.48)	44	0.41 (0.34 to 0.51)
BMS	WL test	–	–	12	−0.43 (−0.52 to −0.40)

For each correlation, the total number of surface vertices of the DG showing a significant correlation (P < 0.05) (Pearson correlation coefficient) with the variable of interest as well as the means and ranges of r values for the significant vertices are provided.

NGMV = normalized gray matter volume; NWMV = normalized white matter volume; LV = lesion volume; WL = word learning; SS = short story.