Figure 3.

Relationship between pupil diameter and BOLD activity without spatial smoothing. A, Whole‐brain map showing brain regions whose unsmoothed BOLD activity covaried with pupil diameter at rest, during oddball task performance, and the overlap between both runs. B, Dorsal pontine activation cluster from the task run (hotter colors indicate higher F values) overlayed on the group‐mean high‐resolution T1 TSE structural image and highlighting overlap with the LC atlas [Keren et al., 2009]. At rest, no dorsal pontine voxels survived whole‐brain correction for multiple comparisons. For A and B, images shown are thresholded at P < 0.001 uncorrected, and all regions survived topological FDR correction for multiple comparisons (P < 0.05). [Color figure can be viewed in the online issue, which is available at http://wileyonlinelibrary.com.]