Table 2.

Classification performance on the ADNI reference data for the voxel‐ and region‐wise approaches compared with the performances on the same data reported by Cuingnet et al. [2011]

Study	Method	AUC (%)	Sens. (%)	Spec. (%)	Sum
This study	Voxel	89	85	79	165
Cuingnet et al.	Voxel‐Direct‐D‐gm	95	81	95	176
This study	Region	90	83	90	172
Cuingnet et al.	Voxel‐Atlas‐D‐gm	92	78	91	169

The method Voxel‐Direct‐D‐gm is similar to our voxel‐wise method, using modulated GM maps, and the method Voxel‐Atlas‐D‐gm is similar to our method region, using features for a set of ROIs. Performance measures were area under the ROC curve (AUC), sensitivity (Sens.), specificity (Spec.), and the sum of sensitivity and specificity (Sum).