Table 5.
Brain Region | Side | Cluster Sizes | Voxels with maximum effect | |||
---|---|---|---|---|---|---|
Talairach | t‐value | |||||
x | y | z | ||||
A. MWoA > HC (val homozygotes) No between‐group differences | ||||||
B. MWoA < HC (val homozygotes) | ||||||
Medial Frontal Gyrus | L | 95 | −3 | 34 | −12 | −4.91 |
R | 20 | 15 | 39 | 17 | −4.43 | |
Middle Frontal Gyrus | L | 22 | −36 | 23 | 46 | −5.05 |
Superior Frontal Gyrus | L | 54 | −6 | 32 | 56 | −5.18 |
R | 10 | 12 | 48 | 25 | −4.4 | |
Precentral Gyrus | L | 13 | −59 | −15 | 42 | −4.78 |
R | 7 | 53 | −12 | 42 | −4.05 | |
Anterior Cingulate | L | 32 | −6 | 46 | −5 | −4.64 |
R | 20 | 3 | 47 | −2 | −4.58 | |
Mid Cingulate | L | 32 | −3 | −19 | 29 | −4.74 |
Insula | L | 31 | −42 | −9 | 0 | −4.64 |
R | 67 | 42 | −11 | 17 | −5.42 | |
Thalamus | L | 8 | −15 | −17 | 15 | −4.3 |
R | 6 | 9 | −6 | 3 | −4.12 | |
Amygdala | R | 6 | 24 | −1 | −18 | −4.28 |
Postcentral Gyrus | L | 15 | −53 | −18 | 45 | −4.56 |
R | 40 | 42 | −21 | 45 | −4.81 | |
C. MWoA > HC (met carriers) | ||||||
Precentral Gyrus | L | 25 | −53 | −1 | 44 | 4.96 |
R | 8 | 56 | −4 | 44 | 4.31 | |
Posterior Cingulate | L | 40 | −6 | −66 | 12 | 5.1 |
R | 46 | 21 | −66 | 12 | 5.39 | |
Precuneus | L | 21 | −3 | −72 | 23 | 4.74 |
R | 11 | 3 | −72 | 23 | 4.52 | |
Occipital cortices | L | 403 | −6 | −69 | 15 | 5.37 |
R | 457 | 9 | −72 | 12 | 5.51 | |
D. MWoA < HC (met carriers) No between‐group differences |