Table 1.

Subject demographics

	M/F	Age (years)	DD (years)	EDSS	NBV (cc)	T2LV (cc)	cThx (mm)
NC	4/8	44 (28–60)	—	—	1510.6 (1397.6–1685.6)	—	2.43 (2.27–2.56)
RR	4/8	45 (30–59)	13 (1–33)	2.5 (1.0–4.0)	1491.2 (1299.6–1661.2)	7.6 (0.8–27.3)	2.42 (2.29–2.53)
SP	4/8	47 (30–62)	14 (3–26)	5.7 (3.5–8.0)	1461.7 (1335.0–1581.7)	33.1 (4.0–80.1)	2.25 (1.89–2.44)

All values are mean (range). DD: disease duration; EDSS: Kurtzke's‐expanded disability status scale; T2LV: manually identified white matter lesion volume on the T2‐weighted scan; NBV: normalized brain volume output using SIENAx; cThx: global cortical thickness; NC: normal controls; SP: secondary‐progressive; RR: relapsing‐remitting.