Average blood oxygen level‐dependent (BOLD), cerebral blood flow‐weighted (CBF), and CBV‐weighted (CBV), signal time course in M1 associated with cued hand movements (gray bars). Error bars represent standard error in each group. Reproduced with permission from Blicher et al., J Cereb Blood Flow Metab, 2012, Vol. 32, 2044–2054, © Macmillan Publishers.