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. Author manuscript; available in PMC: 2019 Nov 21.
Published in final edited form as: ChemMedChem. 2018 Sep 25;13(20):2240–2248. doi: 10.1002/cmdc.201800433

Figure 7.

Figure 7.

Illustrative description of crosslinking of cell wall peptidoglycan in MRSE. The PBPs complete the crosslinking process unless inhibited by β-lactam antibiotics. One mechanism of β-lactam resistance is the expression PBP2a for cell wall crosslinking in the presence of β-lactams.