Table 3.

Mean striatal DTI parameters. Values are of left and right striatum together. MD, AD and RD are shown ×10³ for readability

	Healthy controls	preHD (A and B)	preHD‐A	preHD‐B	Manifest HD
N	24	22	11	11	10
MD	0.686 (0.075)	0.695 (0.037)	0.648 (0.044)	0.758 (0.043)	0.816 (0.045)Φ**
AD	1.130 (0.093)	1.177 (0.027)¤	1.127 (0.032)	1.227 (0.031)϶**	1.235 (0.034)Φ**
RD	0.658 (0.108)	0.641 (0.039)	0.595 (0.048)	0.684 (0.047)	0.764 (0.049)Φ*

Data is shown as mixed model‐based estimates of the group means corrected for age (S.E.)

Φ significantly different from controls and preHD, ϶ significantly different from controls and preHD‐A, ¤ P = 0.08 (compared to controls), *P ≤ 0.05 **P ≤ 0.01, bold values indicate sustained significant difference following Bonferroni correction (P ≤ 0.0125).

MD = mean diffusivity; AD = axial diffusivity; RD = radial diffusivity.