Table 1.
Demographic, clinical, and MRI measures for MS patients and healthy subjects
| MS patients, n = 86 | Healthy subjects, n = 21 | P value | |||
|---|---|---|---|---|---|
| Mean | ±SD | Mean | ±SD | ||
| Age (in years) | 41.58 | 8.82 | 42.48 | 10.29 | >0.05 |
| Gender (F in %) | 61.9% | 65.1% | >0.05 | ||
| Disease duration (years) | 7.15 | 2.11 | |||
| Disease type (RR/SP/PP) | 68/5/9 | — | — | ||
| EDSS (median and range) | 2.5 | (0–6.5) | — | — | |
| Cognition (Z‐score) | −0.83 | 0.76 | 0.06 | 0.48 | <0.001 |
| Thalamic volume (mL) | 18.91 | 2.17 | 20.10 | 1.29 | <0.001 |
| NBV (L) | 1.47 | 0.07 | 1.53 | 0.07 | <0.001 |
| NGMV (L) | 0.82 | 0.05 | 0.84 | 0.05 | <0.001 |
| NDGMV (mL) | 58.60 | 6.18 | 64.79 | 4.25 | <0.001 |
| T1 lesion load | 2.00 | 2.36 | — | — | |
| T2 lesion load | 4.50 | 5.35 | — | — | |
Abbreviations: R, relapsing‐remitting; S, secondary‐progressive; P, primary‐progressive; NBV, normalized brain volume; NGMV, normalized GM volume; NDGMV, normalized deep gray matter volume.