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Tract based spatial statistics: FA versus disease duration and upper motor neuron (UMN) clinical score. Regions of significant correlations between FA and disease duration or UMN score in patients with primary lateral sclerosis (PLS) and amyotrophic lateral sclerosis (ALS) are overlaid on the axial sections of a FA template in the MNI standard space. Results are shown in neurological convention (left is left), at P < 0.05, Family Wise Error (FWE)‐corrected.
