Table 1.

Demographic and clinical characteristics for TS participants

Participant number	Age	Sex	Education	Comorbid diagnoses	YGTSS‐TTS	Y‐BOCS	Medications at time of scan	Past medications (listed in reverse chronological order)
1	28	M	College	None	30	12	Nil	6 months prior to scan, 1 month trial of aripiprazole 4 mg daily; >3 years prior to scan: clonazepam, ziprasidone, tetrabenazine, ropinirole, pergolide, risperidone, carbidopa/levodopa, clonidine, buproprion, donepezil, quetiapine, pimozide, haloperidol, nitrazepam
2	43	M	University	None, OCS	13	13	Nil	Nil
3	29	M	High school	OCS, ADHD	38	12	Nil	10 months prior to scan: ziprasidone, aripiprazole, buproprion, methylphenidate, haloperidol
4	33	F	University	None	8	0	Nil	Nil
5	55	M	University	None	26	6	Nil	Nil
6	23	M	University	ADHD, LD	9	11	Nil	Methylphenidate brief trial at age 7
7	18	M	University	None	31	0	Nil	Clonidine × 1 year, discontinued 3 months prior to scan
8	38	M	College	OCD, ADHD, substance abuse (past)	9	19	Clonidine	Clonidine 0.15 mg daily, started 1 month prior to scan
9	30	M	University	None, mild OCS	16	0	Nil	Nil
10	29	M	University	OCD, MDD (past), substance abuse (past)	23	19	Nil	Dextroamphetamine/amphetamine 20 mg for 3 months, discontinued 3 months prior to scan; paroxetine >2 years prior to scan
11	28	F	High school	OCD, ADHD, asthma, subclinical hyperthyroidism	16	26	Albuterol, fluticasone, acetaminophen/codeine	4 months prior to scan: escitalopram 10 mg × 3 weeks; prior to this: sertraline, mirtazapine, melatonin, clonidine, methylphenidate, carbidopa/levodopa, trazodone, zopiclone, domperidone, imipramine, risperidone

M, male; F, female; OCS, obsessive‐compulsive symptoms; ADHD, attention deficit/hyperactivity disorder; LD, learning disability; OCD, obsessive‐compulsive disorder; MDD, major depressive disorder; YGTSS‐TTS, Yale Global Tic Severity Scale‐Total Tic Score; Y‐BOCS, Yale‐Brown Obsessive Compulsive Scale.