Table 1.
Comparing results of fMRI parameters between patients and controls
| Brain regions | L mTLE versus HC (MNI: x, y, z; peak t values) | R mTLE versus HC (MNI: x, y, z; peak t values) | ||||
|---|---|---|---|---|---|---|
| ALFF | FCD | ALFF‐FCD contrast | ALFF | FCD | ALFF‐FCD contrast | |
| LmTL | −33, −28,24; 5.85 | −24, −30, −21; −3.66 | −27, −30, −21; 6.68 | −24, −27, −15; 2.96 | −21, −12, −27; −2.74 | −24, −27, −18; 4.18 |
| RmTL | 33, −27, −24; 4.18 | 21, −18, −24; −2.17 | 30, −21, −21; 5.58 | 27, −30, −9; 3.59 | 27, −15, −20; −3.16 | 30, −27, −24; 5.68 |
| L lTL | −60, −39, −6; −4.89 | −54,0, −27; −5.27 | −51,9, −33; 4.71 | −57, −12, −18; −3.77 | −60, −3, −20; −3.82 | −42,12, −39; 3.99 |
| R lTL | 60, −39, −6; −3.54 | 57,0, −27; −3.68 | 48, −3, −33; 2.65 | 60, −12, −24; −4.78 | 60, −9, −24; −5.64 | 54, −3, −39; 6.32 |
| L ins | −36,3, −12; 4.41 | −39, −3, −12; −4.08 | −39, −3, −12; 4.65 | −36,3, 12; 3.11 | −39, 0, −12; −2.58 | −39,0, −12; 3.54 |
| R ins | 33,6, −12; 4.00 | 42, −3, 9; −3.19 | 39, −6, −9; 3.23 | 33,3, −12; 4.91 | 45, −3,6; −4.54 | 39, −6, 9; 5.08 |
| L Tha | 16, −9,9; 5.08 | — | — | −15, −12,18; 4.04 | — | −12, −18,9; 2.98 |
| R Tha | 9, −9,9; 3.69 | — | — | 9, −18,9; 2.89 | — | — |
| PCC | 0, −60,33; −6.90 | −1, −58, 33; −4.35 | −6, −54,36; −3.05 | 3, −63, 30; −4.46 | −9, −48,51; −3.23 | 3, −72,39; −3.47 |
| L IPS | −42, −66,30; −5.79 | −42, −69,27; −4.17 | — | −27, −51,48; −3.28 | −39, −60,39; −3.62 | — |
| R IPS | 42, −69,30; −4.24 | 39, −60,27; −3.80 | — | 27, −45, 45; −3.70 | 48, −75, 27; −4.06 | — |
| L IPL | −57, −51,39; −6.62 | −36, −39,48; −3.53 | — | −39, −60,33; −3.30 | −36, −45,51; −3.25 | — |
| R IPL | −51, −42,48; −3.64 | −33, −39,45; −4.23 | — | 45, −72, 27; −4.51 | 39, −36,54; −3.33 | — |
| L PCA | −36, −18,48; 5.50 | −33, −15,54; 4.11 | — | −36, −21,48; 3.74 | −33, −21,45; 2.39 | — |
| R PCA | 36, −18,42; 4.92 | 33, −21, 54; 2.46 | — | 45, −12,51; 5.86 | 39, −15,33; 3.60 | — |
LmTL: left mesial temporal lobe, RmTL: right mesial temporal lobe, L lTL: left lateral mesial temporal lobe, R lTL: right lateral temporal lobe, L ins: left insula, R ins: right insula, PCC: posterior cingulate cortex, L IPS: left intra‐parital sulus, R IPS: right intra‐parital sulus, L IPL: left inferior parietal lobular, R IPL: right inferior parietal lobular, L PCA: left precentral area, R PCA: right precentral area; L mTLE: left‐sided mesial temporal lobe epilepsy, R mTLE: right‐sided mesial temporal lobe epilepsy, HC: Healthy controls; ALFF: amplitude of low‐frequency fluctuation, FCD: functional connectivity density.