Figure 3.

(A) Activation in the left caudate nucleus (x, y, z = −10, 10, 18) during LTM updating was observed for younger carriers and noncarriers of the DRD2/ANKK1‐Taq1a polymorphism, and older noncarriers. (B) Older carriers had significantly reduced activation in this region, as indicated by the gene by age interaction. Activation was considered significant at P < 0.001 uncorrected. (C) Main effect of the DRD2/ANKK1‐Taq1a polymorphism on LTM updating activation in the caudate nucleus for younger and older adults, respectively. [Color figure can be viewed in the online issue, which is available at http://wileyonlinelibrary.com.]