Table 3.

Regions showing a significant negative correlation with the increase in plasma glucose and insulin 30 and 120 min after glucose ingestion

			MNI‐coordinatesb
Region	Hemisphere	Brodmann's area	X	Y	Z	z‐value	k
Plasma glucose a brain response to high caloric food cues 30 min post load
Hypothalamus	R/L		±9	0	−6	2.96a	7
Plasma insulin a brain response to high caloric food cues 120 min post load
Inferior frontal gyrus	R	47	48	42	−12	4.66	144
Middle frontal gyrus	R	8	33	15	42	4.44	183
Cingulate gyrus	R	32	12	24	42	4.38	128
Inferior parietal gyrus	L	40	48	−60	42	4.10	164

Results of multiple regression analyses. The brain's post load response (glucose day) (fMRI 30 – fMRI basal) (fMRI 120 – fMRI basal) to food cues was correlated with the change in plasma glucose and insulin and subjective feeling of hunger (P 0.05, corrected for multiple comparisons)

^a(small volume corrected).

No significant correlation was observed for subjective feeling of hunger.

^bMontreal Neurological Institute.