Table 2.
Contrast | Regions | Hemisphere | MNI coordinates | Number of voxels | ||
---|---|---|---|---|---|---|
x | y | z | ||||
AD and controls | Frontal pole | Right | 16 | 70 | −4 | 1204 |
Middle temporal gyrus | Right | 64 | −32 | −8 | 1143 | |
Precuneus, posterior cingulate cortex | Bilateral | 4 | −54 | 22 | 672 | |
Supramarginal gyrus | Left | −38 | −34 | 36 | 620 | |
Hippocampus (anterior and posterior) | Left | −24 | −16 | −24 | 579 | |
Inferior temporal gyrus | Right | 62 | −58 | −22 | 474 | |
Superior frontal gyrus | Right | 12 | 20 | 40 | 456 | |
Inferior temporal gyrus | Left | −60 | −22 | −32 | 380 | |
Orbitofrontal cortex | Left | −26 | 18 | −12 | 368 | |
Precuneus cortex | Right | 6 | −76 | 56 | 348 | |
Parahippocampal gyrus | Right | 26 | −4 | −38 | 312 | |
Temporal pole | Right | 22 | 6 | −28 | 211 | |
Postcentral gyrus | Left | −54 | −22 | 24 | 189 | |
Middle temporal gyrus | Left | −48 | −50 | 6 | 176 | |
Hippocampus, thalamus | Right | 20 | −34 | −4 | 144 | |
Precentral gyrus | Right | 30 | 10 | 28 | 112 | |
bvFTD and controls | Paracingulate gyrus, anterior cingulate cortex | Bilateral | 0 | 46 | 2 | 1173 |
Temporal pole | Right | 34 | 24 | −34 | 1037 | |
Orbitofrontal cortex | Left | −10 | 24 | −26 | 247 | |
Hippocampus (anterior) | Right | 28 | −12 | −20 | 127 |
All results uncorrected at P < 0.001; only clusters with at least 100 contiguous voxels included. All clusters reported t > 3.9. MNI = Montreal Neurological Institute.