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. 2015 May 9;36(8):3020–3037. doi: 10.1002/hbm.22825

Figure 5.

Figure 5

Relationships between right and left whole hippocampal shape and APOE4 ε4 status (with age, sex, and years of education included in the model) in ε4 carriers relative to noncarriers. Blue colour maps on the hippocampal surfaces indicate inward displacement after 10–15% FDR correction; red colour maps indicate outward displacement after 10–15% FDR correction. Inward surface displacements were observed in ε4 carriers relative to noncarriers along the medial hippocampal head, especially (i) the base of the hippocampal uncus (CA1); (ii) the antero‐medial portion of the hippocampal body (CA2/CA3); and (iii) the medial side of the hippocampal uncus (SR/SL/SM). Outward surface displacements were also observed in both hemispheres in the hippocampal head, particularly on (iv) the anterior portion of the inferior surface (subiculum); and (v) the inferior surface of the uncus (SR/SL/SM). (vi) Some outward displacements were also observed on the lateral surface of the uncus in the left hemisphere (SR/SL/SM).