Table 6.

Differences in slow‐5 and slow‐4 amplitude of low frequency fluctuations (fALFF) bands in heroin and placebo treatment

Brain region	Cluster size (voxels)	Cluster P‐value (FWE corrected)	MNI coordinats (x, y, z)	Hemisphere	Z‐value at voxel level
fALFF slow‐5: Heroin > Placebo Treatment
Precentral Gyrus	1305	<0.001	2, −20, 70	R	4.29
Precentral Gyrus			20, −28, 66	R	4.22
Precentral Gyrus			6, −28, 70	R	4.13
fALFF slow‐5: Heroin < Placebo Treatment
None
fALFF slow‐4: Heroin > Placebo Treatment
Thalamus	814	<0.001	8, −8, 4	R	4.96
Thalamus			−8, −12, 8	L	4.97
Thalamus			8, −24 4	R	3.90
fALFF slow‐4: Heroin < Placebo Treatment
None

fALFF slow‐4: 0.027–0.073 Hz; fALFF slow‐5: 0.01–0.027 Hz; FWE: family‐wise error; L: left; R: right.