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. 2014 Feb 24;35(9):4345–4361. doi: 10.1002/hbm.22479

Figure 3.

Figure 3

CCEP connectivity pattern to map perisylvian language areas (Patient 4). Under general anesthesia, single‐pulse ES was delivered to four candidate sites (Plate B) according to the noninvasive anatomo‐functional mapping, and CCEPs were recorded from the temporoparietal area (Plate A). Two trials are plotted in superimposition at each electrode. The vertical bar corresponds to the time of stimulation. Note the CCEP pattern in Plate A differs evidently among the four stimulus sites. Electrode B05–13 stimulation showed the largest and most discrete CCEP response in the lateral temporoparietal area (Electrode A04 and A05). This site was regarded as the putative anterior language area. Indeed 50 Hz stimulation of this area showed language impairment in the awake condition. n.a. = CCEP was not available due to high impedance in the recording electrode. Other conventions are the same as for Figure 1.