Figure 2.

Structural networks were explored using graph theory through the following steps: (A) First, for each DTI dataset a whole‐brain tractography was performed using ExploreDTI. (B) Then, we defined the network nodes as the regions of the AAL template for each hemisphere. Each hemispheric network contained the same number of homologous regions of the AAL, that is, 45 regions. (C) We next determined a continuous measure of association between nodes. This was the percentage of tracts between each pair of regions of the AAL template, resulting in two 45 × 45 connectivity matrices for each subject, one for the left hemisphere and the other for the right hemisphere. Finally, from the hemispheric networks, measures of local and global connectivity were computed. [Color figure can be viewed in the online issue, which is available at http://wileyonlinelibrary.com.]