Table 1.
FA results
| # | P | Voxels | X | Y | Z | Atlas |
|---|---|---|---|---|---|---|
| IGE < controls | ||||||
| 7 | 0.003 | 6,368 | −17 | −26 | 32 | Body of corpus callosum |
| 7 | 0.004 | −20 | −34 | 53 | Corticospinal tract L | |
| 7 | 0.004 | −20 | −25 | 48 | Corticospinal tract L | |
| 7 | 0.004 | −22 | −45 | 38 | Superior longitudinal fasciculus L | |
| 7 | 0.004 | −19 | −22 | 37 | Corticospinal tract L | |
| 7 | 0.004 | −17 | −12 | 36 | Body of corpus callosum | |
| 7 | 0.004 | −17 | 12 | 35 | Superior corona radiata L | |
| 7 | 0.004 | −18 | −35 | 35 | Cingulum (cingulate gyrus) L | |
| 7 | 0.004 | −15 | 0 | 34 | Body of corpus callosum | |
| 7 | 0.004 | −11 | −15 | 30 | Body of corpus callosum | |
| 7 | 0.004 | −14 | −26 | 29 | Body of corpus callosum | |
| 7 | 0.004 | 11 | −18 | 28 | Body of corpus callosum | |
| […] plus 58 additional subclusters | ||||||
| 6 | 0.009 | 43 | −29 | 2 | −34 | Cingulum (hippocampus) L |
| 6 | 0.01 | −35 | −1 | −29 | Inferior longitudinal fasciculus L | |
| 5 | 0.009 | 35 | −31 | −64 | 35 | (Parietal lobe L) |
| 5 | 0.01 | −30 | −62 | 38 | (Parietal lobe L) | |
| 5 | 0.01 | −34 | −68 | 31 | Inferior longitudinal fasciculus L | |
| 4 | 0.01 | 16 | −30 | −83 | 16 | Inferior longitudinal fasciculus L |
| 3 | 0.01 | 10 | −29 | −77 | 12 | Inferior longitudinal fasciculus L |
| 2 | 0.01 | 9 | −33 | −79 | 16 | Inferior longitudinal fasciculus L |
| 1 | 0.01 | 2 | −34 | −67 | 26 | (Parietal lobe L) |
| IGE > controls | ||||||
| No significant differences | ||||||
| JME < controls | ||||||
| 5 | 0.001 | 11,507 | 8 | −19 | 26 | Body of corpus callosum |
| 5 | 0.002 | 25 | −21 | 34 | Corticospinal tract R | |
| 5 | 0.002 | 23 | −43 | 34 | Superior longitudinal fasciculus R | |
| 5 | 0.002 | −15 | 9 | 30 | Body of corpus callosum | |
| 5 | 0.002 | 13 | 4 | 30 | Body of corpus callosum | |
| 5 | 0.002 | −14 | −23 | 30 | Body of corpus callosum | |
| 5 | 0.002 | 15 | 13 | 29 | Body of corpus callosum | |
| 5 | 0.002 | 11 | −4 | 29 | Body of corpus callosum | |
| 5 | 0.002 | 26 | −34 | 29 | Superior longitudinal fasciculus R | |
| 5 | 0.002 | 16 | −35 | 29 | Splenium of corpus callosum | |
| 5 | 0.002 | 10 | −16 | 28 | Body of corpus callosum | |
| 5 | 0.002 | −9 | −17 | 27 | Body of corpus callosum | |
| […] plus 122 additional subclusters | ||||||
| 4 | 0.008 | 1,521 | 27 | 10 | 24 | Superior corona radiata R |
| 4 | 0.008 | 25 | 12 | 34 | (Frontal lobe R) | |
| 4 | 0.008 | 30 | 3 | 30 | Superior longitudinal fasciculus R | |
| 4 | 0.008 | 29 | 22 | 27 | (Frontal lobe R) | |
| 4 | 0.008 | 27 | 29 | 22 | Anterior thalamic radiation R | |
| 4 | 0.009 | 23 | 0 | 34 | Superior corona radiata R | |
| 4 | 0.009 | 37 | 2 | 26 | Superior longitudinal fasciculus (temporal part) R | |
| 4 | 0.009 | 29 | 27 | 14 | Inferior fronto‐occipital fasciculus R | |
| 4 | 0.009 | 30 | 37 | 12 | Anterior thalamic radiation R | |
| 4 | 0.009 | 37 | 32 | 11 | Inferior fronto‐occipital fasciculus R | |
| 4 | 0.009 | 33 | 48 | 7 | Anterior thalamic radiation R | |
| […] plus 10 additional subclusters | ||||||
| 3 | 0.009 | 253 | 32 | −1 | 17 | Superior longitudinal fasciculus R |
| 3 | 0.01 | 28 | −9 | 26 | Corticospinal tract R | |
| 3 | 0.01 | 35 | −3 | 22 | Superior longitudinal fasciculus R | |
| 3 | 0.01 | 27 | −2 | 20 | Superior longitudinal fasciculus R | |
| 3 | 0.01 | 33 | 4 | 18 | Superior longitudinal fasciculus R | |
| 2 | 0.009 | 95 | 19 | 33 | 27 | Forceps minor |
| 2 | 0.01 | 19 | 24 | 32 | (Frontal lobe R) | |
| 2 | 0.01 | 21 | 34 | 27 | Forceps minor | |
| 2 | 0.01 | 22 | 40 | 20 | Anterior thalamic radiation R | |
| 1 | 0.01 | 19 | 18 | 47 | 20 | Forceps minor |
| 1 | 0.01 | 18 | 45 | 21 | Forceps minor | |
| JME > controls | ||||||
| No significant differences | ||||||
| JME + IGE < controls | ||||||
| 1 | 0.001 | 32,076 | 3 | −27 | 23 | Body of corpus callosum |
| 1 | 0.001 | −21 | −47 | 38 | Superior longitudinal fasciculus L | |
| 1 | 0.001 | −19 | −22 | 37 | Corticospinal tract L | |
| 1 | 0.001 | −19 | −33 | 35 | Posterior corona radiata L | |
| 1 | 0.001 | −15 | −28 | 30 | Body of corpus callosum | |
| 1 | 0.001 | 14 | −26 | 29 | Anterior thalamic radiation R | |
| 1 | 0.001 | −6 | −13 | 26 | Body of corpus callosum | |
| 1 | 0.001 | 3 | −14 | 25 | Body of corpus callosum | |
| 1 | 0.001 | −7 | −24 | 25 | Body of corpus callosum | |
| 1 | 0.002 | −6 | −10 | 63 | (White matter of the supplementary motor area L) | |
| 1 | 0.002 | −11 | −2 | 62 | (White matter of the supplementary motor area L) | |
| […] plus 339 additional subclusters | ||||||
| JME + IGE > controls | ||||||
| No significant differences | ||||||
| JME > IGE | ||||||
| No significant differences | ||||||
| JME < IGE | ||||||
| No significant differences | ||||||
Detected clusters of significant (P < 0.01, corrected) FA differences. For each cluster (unique cluster index = #) the 10 most significant subclusters (local maxima with a minimal distance of 8 mm) are also listed. The anatomical position was estimated using the “JHU White‐Matter Tractography Atlas” supplied with FSL. When no label was found in the former, the “JHU ICBM‐DTI‐81 White‐Matter Labels” atlas was used instead. When both atlases reported no anatomical label a visual assessment was done, these labels are printed in brackets. L = left, R = right, WM = white matter, P = corrected P value, voxels = number of voxels in this cluster, X, Y, Z = coordinates in MNI space (mm).