Table 2.

TBSS RD and AD results

#	P	Voxels	X	Y	Z	Atlas
RD: JME + IGE < controls
No significant differences
RD: JME+IGE > controls
1	0	35,851	−41	−37	5	Superior longitudinal fasciculus (temporal part) L
1	0.001		9	−41	64	(Precentral gyrus R)
1	0.001		−12	−27	62	Corticospinal tract L
1	0.001		17	−22	61	Corticospinal tract R
1	0.001		15	−37	59	Corticospinal tract R
1	0.001		−11	−34	58	(Precentral gyrus L)
1	0.001		15	−9	56	(White matter of the supplementary motor area R)
1	0.001		15	−28	56	Corticospinal tract R
1	0.001		−18	−41	56	Corticospinal tract L
1	0.001		21	−49	56	Superior longitudinal fasciculus R
1	0.001		−15	−9	54	(White matter of the supplementary motor area L)
1	0.001		14	7	52	(White matter of the supplementary motor area R)
[…] plus 402 additional subclusters
AD: JME + IGE < controls
No significant differences
AD: JME + IGE > controls
No significant differences

Detected clusters of significant (P < 0.01, corrected) RD or AD differences. For each cluster (unique cluster index = #) the 10 most significant subclusters (local maxima with a minimal distance of 8 mm) are also listed. The anatomical position was estimated using the “JHU White‐Matter Tractography Atlas” supplied with FSL. When no label was found in the former, the “JHU ICBM‐DTI‐81 White‐Matter Labels” atlas was used instead. When both atlases reported no anatomical label a visual assessment was done, these labels are printed in brackets. L = left, R = right, WM = white matter, P = corrected P value, voxels = number of voxels in this cluster, X, Y, Z = coordinates in MNI space (mm).