Table I.
Cross‐validation results for the decoding of picture categories in binge‐eating patients, bulimic patients, and healthy control subjects
| Group/Region | H | CS | x | y | z | DA (%) | P | Mean t‐value | Mean beta‐values | Vox* (%) |
|---|---|---|---|---|---|---|---|---|---|---|
| BED | ||||||||||
| ACC | L | 16 | −10 | 42 | −4 | 88.2 | <10−5 | 1.7 | −0.2/−0.7 | 0 |
| 13 | 0 | 50 | 0 | 82.4 | <10−3 | 1.3 | −0.3/−0.8 | 0 | ||
| R | 60 | 10 | 42 | 12 | 88.2 | <10−5 | 1.1 | −0.1/−0.4 | 3 | |
| Amygdala | R | 3 | 28 | 4 | −16 | 88.2 | <10 −5 | 1.0 | 0.5/0.2 | 0 |
| Insula | L | 34 | −40 | −10 | 6 | 88.2 | <10−5 | 0.1 | 0.1/0.1 | 0 |
| lat. OFC | L | 7 | −26 | 38 | −16 | 88.2 | <10−5 | 1.9 | 0.5/−0.1 | 10 |
| R | 9 | 32 | 26 | −8 | 85.3 | <10−4 | 0.3 | 0.3/0.2 | 0 | |
| v. Striatum | L | 2 | −4 | 6 | −8 | 82.4 | <10−3 | 1.2 | 0.1/−0.3 | 0 |
| BUL | ||||||||||
| ACC | L | 7 | −6 | 38 | 20 | 85.7 | <10−3 | 1.3 | 0.1/−0.3 | 0 |
| 7 | 0 | 24 | 30 | 85.7 | <10−3 | 3.0 | 0.5/−0.5 | 16 | ||
| 6 | −6 | 32 | 26 | 89.3 | <10−4 | 2.8 | 0.4/−0.4 | 10 | ||
| R | 6 | 10 | 48 | 10 | 82.1 | <10−3 | 1.0 | 0.0/−0.3 | 0 | |
| 5 | 4 | 28 | 14 | 82.1 | <10−3 | 1.8 | 0.1/−0.4 | 0 | ||
| Amygdala | L | 46 | −26 | −2 | −20 | 96.4 | <10−6 | 2.1 | 0.5/0.0 | 2 |
| Insula | L | 19 | −38 | −4 | −2 | 92.9 | <10−5 | 2.6 | 0.5/−0.1 | 17 |
| 18 | −38 | 4 | −2 | 89.3 | <10−4 | 1.6 | 0.3/−0.1 | 1 | ||
| R | 7 | 38 | −12 | −6 | 89.3 | <10−4 | 1.4 | 0.3/−0.1 | 4 | |
| 9 | 42 | −12 | 6 | 89.3 | <10−4 | 1.0 | 0.1/−0.2 | 1 | ||
| lat. OFC | L | 99 | −22 | 44 | −20 | 92.9 | <10−5 | 1.6 | 0.5/0.1 | 13 |
| 5 | −36 | 56 | −2 | 92.9 | <10−5 | 0.9 | 0.3/0.0 | 0 | ||
| med. OFC | L | 1 | −20 | 44 | −20 | 89.3 | <10−4 | 0.2 | 0.3/0.3 | 0 |
| 5 | −24 | 60 | −6 | 85.7 | <10−3 | 1.9 | 0.0/−0.6 | 0 | ||
| C‐OW | ||||||||||
| Insula | L | 20 | −44 | −6 | −6 | 85.3 | <10−4 | 0.8 | 0.3/0.1 | 2 |
| R | 24 | 38 | 18 | −14 | 85.3 | <10−4 | 1.5 | 0.7/0.3 | 4 | |
| 5 | 42 | 4 | −6 | 82.4 | <10−3 | 1.8 | 0.5/−0.1 | 4 | ||
| C‐NW | ||||||||||
| Insula | L | 21 | −40 | −4 | 6 | 85 | <10−5 | 1.4 | 0.2/−0.1 | 2 |
| R | 6 | 46 | −6 | −2 | 82.5 | <10−4 | −0.2 | −0.3/−0.3 | 0 | |
| lat. OFC | L | 11 | −24 | 30 | −20 | 82.5 | <10−4 | 3.4 | 1.0/0.1 | 40 |
| med. OFC | L | 1 | −16 | 26 | −14 | 85 | <10−5 | 1.9 | 0.2/−0.1 | 5 |
H: hemisphere; CS: cluster size, that is the number of neighboring significant searchlights; x, y, and z: Montreal Neurological Institute coordinate of the center of the searchlight classifier with the peak accuracy; DA(%): decoding accuracy; P: probability of the accuracy according to χ2‐distribution; Mean t‐value for the contrast food minus neutral for voxels underlying (a cluster of) significant searchlight classifier(s); mean beta‐values: mean beta‐regression coefficients for voxels underlying a (cluster of) significant searchlight classifier(s) for food and neutral picture presentation; Vox*(%): percentage of these voxels showing significant results for the contrast (puncorrected = 0.001, no cluster size criterion, two‐sided). ACC: anterior cingulate cortex; OFC: orbitofrontal cortex; lat.: lateral; med.: medial; v: ventral. Non‐bold text indicates a significant decoding accuracy not corrected for multiple comparisons (puncorrected = 0.001, k = 5). Bold text indicates that the accuracy of the classifier with the peak accuracy in a cluster is significant on a FWE‐corrected level (Bonferroni‐correction, i.e., pFWE = 0.05 [α]/total number of searchlight centers in a given ROI).