Figure 3.

Association of regional gray matter with executive performance and age. A: The association between mean gray matter volume within prespecified ROIs (ROI‐VBM analysis) and the respective difference score was assessed by partial correlation (corrected for age and sex). Correlations are illustrated using color coding as indicated. Note that smaller difference scores indicate better executive performance. All correlations were negative, i.e. better performance, indicated by smaller difference scores, was associated with larger gray matter volume within the respective ROIs. B: Gray matter decrease within prespecified ROIs per 10 years of age was assessed using linear regression (corrected for sex), converted to percentage using the gray matter volume of a 50‐year‐old male as extrapolated from the linear regression as reference. *Significant at P < 0.05 (uncorrected); ^§significant at P < 0.05 after Bonferroni correction. [Color figure can be viewed in the online issue, which is available at http://wileyonlinelibrary.com.]