Table II.

Brain regions with significant changes in gray matter volume after stroke

Location	Hemisphere	Local maximum				Cluster size (voxel)
		Z‐value	x	y	z
Increased
Mid‐cingulate cortex	IL	6.02	−6	−28	33	577
Hippocampus	CL	5.73	24	−31	−2	313
Precuneus lobe	CL	5.54	10	−48	13	591
Precuneus lobe	IL	5.36	−15	−49	9	175
Lingual gyrus	IL	5.17	−17	−80	−5	316
Cerebellum VI	IL	5.16	−18	−74	−21	331
Decreased
Precentral gyrus	IL	5.57	−55	−7	43	8,684
Precentral gyrus	CL	5.20	0	−32	56	2,508
Postcentral gyrus	IL	5.37	−54	−11	40	9,492
Postcentral gyrus	CL	4.29	18	−37	71	410
Premotor cortex	IL	5.38	−53	−6	44	6,564
Mid‐cingulate cortex	IL	5.92	−5	−40	55	4,282
Mid‐cingulate cortex	CL	5.09	5	3	30	1,624
Middle frontal gyrus	IL	4.45	−25	64	11	427
Posterior cingulate cortex	IL	4.44	−4	59	3	124
Posterior cingulate cortex	IL	4.97	−3	−41	17	122
Hippocampus	IL	4.94	−31	−40	−2	4,328
Parahippocampus	CL	4.62	36	−41	−3	211
Caudate	CL	4.39	14	5	10	255
Cuneus lobe	CL	4.28	19	−82	44	359
Superior frontal gyrus	IL	4.22	−25	46	12	342
Middle frontal gyrus	IL	3.79	−23	16	41	162
Superior frontal gyrus	IL	3.78	−16	43	46	209
Middle temporal gyrus	CL	3.96	45	−66	18	201
Superior temporal gyrus	CL	4.20	49	−49	19	826
Angular gyrus	CL	3.92	51	−63	35	282
Cuneus lobe	CL	3.90	32	−90	25	140
Inferior parietal lobule	CL	3.90	37	−42	42	271
Cerebellum anterior lobe	CL	4.95	8	−51	−38	463
Cerebellum VI	CL	5.70	38	−53	−27	11,517
Cerebellum VIII	CL	4.64	9	−66	−42	404
Cerebelum_Crus1	CL	4.37	10	−87	−23	223

x, y, z represent peak‐value voxel location in the standard MNI space. Z‐value is the maximum Z score of the cluster demonstrating significant longitudinal changes in gray matter volume after stroke.

CL, contralesional hemisphere; IL, ipsilesional hemisphere.