Table II.
Significantly activated regions in continuous shift (S) minus control (C) contrasts in set‐shifting task: MCST‐NF (with negative feedback) and MCST‐IR (with incorrect responses)
| Area | Normal | PDoff | PDon | ||||||
|---|---|---|---|---|---|---|---|---|---|
| x, y, z | t‐stats | Cluster size | x, y, z | t‐stats | Cluster size | x, y, z | t‐stats | Cluster size | |
| MCST‐NF | |||||||||
| DLPFC_R | 30, 56, 8 | 6a, b | 25071 | 32, 26, 34 | 3.43 | 77 | |||
| VLPFC_L | −50, 14, 8 | 3.05 | 30 | ||||||
| VLPFC_R | 52, 12, 32 | 5.96a, b | 230 | ||||||
| Medial PFC_L | 6, 50, 28 | 3.85 | 457 | ||||||
| PMC_L | −42, −4, 40 | 3.5 | 75 | ||||||
| ACC_R | 12, 44, 12 | 3.16 | 53 | ||||||
| MCC_L | −8, −40, −52 | 3.51a | 37 | −16, −32, 46 | 3.38 | 120 | |||
| −8, 14, 44 | 3.69 | 213 | |||||||
| MCC_R | 10, −28, 46 | 3.65a | 245 | 10, 14, 40 | 3.8 | 95 | |||
| Insula_L | −26, 26, −4 | 3.78 | 99 | ||||||
| SSC_L | −32, −38, 52 | 3.39a | 33 | ||||||
| SSC_R | 40, −32, 46 | 3.14a | 36 | ||||||
| AG_R | 42, −56, 34 | 3.74 | 90 | ||||||
| PPC_R | 40, −46, 44 | 3.36 | 52 | ||||||
| PCN_L | −18, −56, 38 | 3.69a | 174 | −10, −46, 50 | 3.07 | 31 | |||
| PCN_R | 4, −60, 22 | 3.26 | 99 | ||||||
| STG_R | 56, −46, 24 | 3.11 | 40 | ||||||
| MTG_L | −52, −52, 22 | 3.27 | 30 | ||||||
| ITG_L | −46, −58, −14 | 4.71a, b | 88 | ||||||
| Caudate_R | 16, 6, 14 | 2.9 | 37 | ||||||
| MCST‐IR | |||||||||
| DLPFC_L | −12, 32, 50 | 3.3 | 43 | −18, −10, 56 | 3.24 | 54 | |||
| DLPFC_R | 18, 14, 44 | 3.14 | 79 | ||||||
| Lateral OBF_R | 36, 30, −10 | 3.41 | 39 | ||||||
| SMA_R | 16, −16, 54 | 3.2 | 50 | ||||||
| Insula_L | −28, 16, −18 | 3.52 | 85 | ||||||
| Insula_R | 38, −2, 2 | 4.05 | 50 | ||||||
| AG_L | −50, −54, 32 | 3.64 | 42 | ||||||
| STP_L | −48, 18, −26 | 3.39 | 63 | ||||||
| HC_R | 26, −46, 0 | 2.98 | 42 | ||||||
| PHG_L | −14, −28, −16 | 4.22 | 87 | ||||||
| PHG_R | 20, −26, −16 | 4.34 | 106 | ||||||
| OC_L | −48, −70, 2 | 3.77 | 40 | ||||||
L, left; R, right; DLPFC, dorsolateral prefrontal cortex; VLPFC, ventrolateral prefrontal cortex; lateral OBF, lateral orbitofrontal cortex; medial PFC, medial prefrontal cortex; PMC, primary motor cortex; SMA, supplementary motor area; ACC, anterior cingulate cortex; MCC, middle cingulate cortex; SSC, somatosensory cortex; AG, angular gyrus; PPC, posterior parietal cortex; PCN, precuneus; STP, superior temporal pole; STG, superior temporal gyrus; MTG, middle temporal gyrus; ITG, inferior temporal gyrus; HC, hippocampus; PHG, parahippocampal gyrus; OC, occipital cortex. Locations identified by anatomical automatic labeling with cluster approach. Peak threshold levels at P < 0.005 (uncorrected). Number denotes t‐statistics. Cluster size = number of activated voxels.
Activations that reach P < 0.05 with FDR corrections.
Activations that reach P < 0.05 with FWE corrections.