Table I.
Brain regions activated by painful CO2 stimuli
| Effect | Left hemispherea | Right hemisphere | ||||||
|---|---|---|---|---|---|---|---|---|
| Region | x | y | z | t value | x | y | z | t value |
| Activations during painful CO2 stimuli | ||||||||
| Insula lobe | −33 | 18 | 6 | 10.36 | 39 | 15 | −6 | 10.11 |
| Insula lobe | −36 | 9 | 3 | 8.81 | 33 | 24 | 3 | 9.29 |
| Insula lobe | −36 | 6 | −6 | 8.41 | 39 | −3 | 6 | 8.87 |
| Insula lobe | −39 | 3 | −9 | 8.37 | — | — | — | — |
| MCC | −9 | 9 | 33 | 9.82 | 6 | 15 | 45 | 7.34 |
| SII | −39 | −9 | 12 | 9.55 | — | — | — | — |
| Postcentral gyrus | −36 | −27 | 51 | 7.95 | — | — | — | — |
| Postcentral gyrus | −60 | −21 | 27 | 7.77 | — | — | — | — |
| Postcentral gyrus | −63 | −18 | 21 | 7.43 | — | — | — | — |
| Precentral gyrus | −51 | 3 | 18 | 8.35 | — | — | — | — |
| IFG | −60 | 6 | 15 | 6.53 | — | — | — | — |
| SMA | −6 | 6 | 51 | 7.46 | — | — | — | — |
a
Contralateral to the stimulus application side.
SII, secondary somatosensory cortex; MCC, Middle cingulate cortex; IFG, Inferior frontal gyrus; SMA, supplementary motor area.
The table contains the anatomic location of the voxels with highest voxel level t in the respective region of a 24‐subject group analysis. Reported voxels are thresholded at P < 0.05 familywise error (FWE) corrected. Coordinates are reported in MNI space.