Table II.
Brain regions activated by the CO2 stimulus irrespective of its intensity and corresponding perception, brain regions coding for stimulus intensity irrespective of the corresponding perception, and brain regions coding exclusively for pain perception
| Effect | Left hemispherea | Right hemisphere | ||||||
|---|---|---|---|---|---|---|---|---|
| Region | x | y | z | t value | x | y | z | t value |
| CO2‐stimulus‐related activation | ||||||||
| Insula lobe | −30 | 21 | 3 | 11.21 | 33 | 21 | 3 | 12.75 |
| Insula lobe | −33 | 18 | 0 | 10.84 | 39 | 0 | 3 | 7.52 |
| Insula lobe | −36 | 6 | −9 | 6.54 | — | — | — | — |
| SMA | −3 | 12 | 48 | 7.25 | 6 | 18 | 48 | 7.78 |
| SMA | — | — | — | — | 12 | 9 | 51 | 7.12 |
| Stimulus intensity‐related activation | ||||||||
| Insula lobe | −33 | −9 | 15 | 9.70 | 45 | 12 | −3 | 7.24 |
| Insula lobe | −36 | −3 | −6 | 8.54 | 51 | 9 | −3 | 6.94 |
| Superior temporal gyrus | −57 | −9 | 6 | 6.73 | 60 | 3 | 3 | 7.10 |
| SII | −45 | −18 | 21 | 7.65 | — | — | — | — |
| SII | −48 | 3 | 12 | 6.71 | — | — | — | — |
| Amygdala (LB) | −27 | 0 | −21 | 8.05 | — | — | — | — |
| Amygdala (SF) | −18 | 0 | −15 | 7.15 | — | — | — | — |
| Postcentral gyrus | −39 | −27 | 54 | 7.67 | — | — | — | — |
| Postcentral gyrus | −57 | −3 | 15 | 7.60 | — | — | — | — |
| Postcentral gyrus | −60 | −15 | 27 | 7.07 | — | — | — | — |
| Postcentral gyrus | −57 | −12 | 30 | 7.02 | — | — | — | — |
| Postcentral gyrus | −63 | −21 | 15 | 7.50 | — | — | — | — |
| MCC | 0 | 12 | 39 | 7.37 | — | — | — | — |
| Pain perception‐related activation | — | — | — | — | ||||
| Precentral gyrus | −39 | −24 | 60 | 8.14 | — | — | — | — |
| Postcentral gyrus | −39 | −33 | 57 | 7.12 | — | — | — | — |
| Insula lobe | −42 | 0 | 9 | 7.83 | — | — | — | — |
| Putamen | — | — | — | — | 33 | 3 | 9 | 6.83 |
a
Contralateral to the stimulus application side.
SII, secondary somatosensory cortex; MCC, Middle cingulate cortex; SMA, supplementary motor area.
The table contains the anatomic location of the voxels with highest voxel level t in the respective region of a 24‐subject group analysis. Reported voxels are thresholded at P < 0.05 family wise error (FWE) corrected. Coordinates are reported in MNI space.