Table XII.
Spatial location and extent of ALE values for study 2 (noxious heat)
Side | Region | BA | x | y | z | ALE value | P value | Cluster # | Volume (mm3) |
---|---|---|---|---|---|---|---|---|---|
Left | Anterior insula | −40 | 18 | 6 | 0.025 | <0.00001 | 1 | 4432 | |
Left | Posterior insula | −44 | −24 | 16 | 0.024 | <0.00001 | |||
Left | Lentiform Nucleus | −22 | 0 | −2 | 0.024 | <0.00001 | |||
Left | Lentiform Nucleus | −22 | −10 | 8 | 0.018 | 0.0004 | |||
Left | Mid‐insula/claustrum | −34 | 4 | 6 | 0.017 | 0.0002 | |||
Left | Anterior insula/claustrum | −34 | 10 | 6 | 0.017 | 0.0002 | |||
Left | Anterior insula | −30 | 18 | 8 | 0.017 | 0.0004 | |||
Left | Lentiform Nucleus | −24 | −4 | 6 | 0.016 | <0.00001 | |||
Left | Posterior insula/claustrum | −34 | −16 | 10 | 0.014 | 0.0006 | |||
Right | Mid‐insula/claustrum | 34 | 4 | 10 | 0.033 | <0.00001 | 2 | 2432 | |
Right | Anterior insula/claustrum | 34 | 12 | 6 | 0.030 | <0.00001 | |||
Right | Thalamus | 12 | −20 | 4 | 0.029 | <0.00001 | 3 | 1544 | |
Right | Thalamus | 10 | −10 | 6 | 0.013 | 0.001 | |||
Left | Cingulate Gyrus | 32 | −4 | 10 | 40 | 0.024 | 0.0002 | 4 | 1288 |
Left | Cingulate Gyrus | 24 | −4 | 12 | 32 | 0.016 | 0.0002 | ||
Right | SII | 40 | 52 | −30 | 22 | 0.021 | 0.0002 | 5 | 1160 |
Right | Posterior insula | 40 | 52 | −22 | 14 | 0.014 | 0.0006 | ||
Right | Lentiform Nucleus | 30 | −14 | 8 | 0.018 | <0.00001 | 6 | 688 | |
Right | Posterior insula | 32 | −10 | 18 | 0.018 | 0.0002 | |||
Right | Cingulate Gyrus | 24 | 2 | −4 | 44 | 0.020 | <0.00001 | 7 | 576 |
Left | Thalamus | −12 | −24 | 12 | 0.022 | <0.00001 | 8 | 552 | |
Right | Inferior Frontal Gyrus | 38 | 46 | 2 | 0.021 | <0.00001 | 9 | 464 | |
Right | Caudate | 16 | 8 | 12 | 0.021 | <0.00001 | 10 | 368 | |
Left | MI | 4 | −32 | −22 | 50 | 0.020 | <0.00001 | 11 | 304 |
Right | Cingulate Gyrus | 32 | 4 | 22 | 26 | 0.018 | <0.00001 | 12 | 256 |
Left | Anterior insula | −46 | 6 | 16 | 0.013 | 0.0006 | 13 | 168 | |
Left | Inferior Frontal Gyrus | 44 | −48 | 0 | 12 | 0.013 | 0.0008 | ||
Right | Middle Frontal Gyrus | 46 | 42 | 36 | 24 | 0.014 | <0.00001 | 14 | 152 |
Right | Superior Frontal Gyrus | 9 | 40 | 34 | 28 | 0.013 | 0.0004 | ||
Right | Anterior insula | 46 | 6 | 16 | 0.014 | 0.0002 | 15 | 144 | |
Right | Inferior Frontal Gyrus | 44 | 52 | 6 | 12 | 0.014 | 0.0006 | ||
Left | Posterior insula | −40 | −4 | 10 | 0.013 | 0.0006 | 16 | 80 | |
Left | Superior Temporal Gyrus | 42 | −54 | −30 | 14 | 0.013 | 0.001 | 17 | 80 |
Right | Thalamus | 6 | −18 | 14 | 0.013 | 0.0008 | 18 | 72 | |
Left | Posterior insula | −52 | −34 | 20 | 0.013 | 0.0006 | 19 | 64 | |
Left | Cingulate Gyrus | 24 | −10 | 4 | 30 | 0.013 | 0.001 | 20 | 64 |
Right | Lentiform Nucleus | 24 | 4 | 16 | 0.014 | 0.0006 | 21 | 56 | |
Right | IPL | 39 | 48 | −62 | 38 | 0.013 | 0.0008 | 22 | 56 |
Left | Medial Frontal Gyrus | 6 | 0 | −10 | 52 | 0.013 | 0.0008 | 23 | 56 |
Right | Lentiform Nucleus | 22 | −4 | 12 | 0.012 | 0.001 | 24 | 48 | |
Right | Posterior insula | 36 | −18 | 20 | 0.012 | 0.001 | 25 | 48 | |
Left | Superior Frontal Gyrus | 6 | −4 | 8 | 60 | 0.013 | 0.0008 | 26 | 48 |
Right | Medial Frontal Gyrus | 6 | 2 | −12 | 62 | 0.011 | 0.003 | 27 | 48 |
Right | Cerebellum | 30 | −76 | −28 | 0.013 | 0.001 | 28 | 40 | |
Right | Cerebellum | 8 | −60 | −12 | 0.012 | 0.001 | 29 | 40 | |
Right | Precentral Gyrus | 6 | 50 | −4 | 38 | 0.012 | 0.001 | 30 | 40 |
Right | SI | 20 | −36 | 52 | 0.013 | 0.001 | 31 | 40 | |
Right | Middle Frontal Gyrus | 6 | 18 | −10 | 58 | 0.013 | 0.001 | 32 | 40 |
Left | Cerebellum | −28 | −40 | −42 | 0.012 | 0.001 | 33 | 32 | |
Right | Cerebellum | 18 | −72 | −30 | 0.012 | 0.001 | 34 | 32 | |
Left | Cerebellum | −20 | −60 | −20 | 0.013 | 0.001 | 35 | 32 | |
Right | Cerebellum | 0 | −52 | −16 | 0.012 | 0.001 | 36 | 32 | |
Right | Inferior Frontal Gyrus | 47 | 42 | 20 | −4 | 0.013 | 0.001 | 37 | 32 |
Right | Posterior insula/claustrum | 36 | −6 | 0 | 0.013 | 0.001 | 38 | 32 | |
Right | Lentiform Nucleus | 20 | 10 | 0 | 0.012 | 0.001 | 39 | 32 | |
Right | SII | 42 | 56 | −12 | 12 | 0.013 | 0.001 | 40 | 32 |
Left | Posterior insula | −48 | −20 | 24 | 0.012 | 0.001 | 41 | 32 | |
Left | IPL | 40 | −62 | −40 | 28 | 0.012 | 0.001 | 42 | 32 |
Right | Cingulate Gyrus | 23 | 4 | −22 | 28 | 0.012 | 0.001 | 43 | 32 |
Right | Medial Frontal Gyrus | 8 | 14 | 30 | 38 | 0.012 | 0.001 | 44 | 32 |
Left | Paracentral Lobule | 5 | −10 | −34 | 46 | 0.012 | 0.001 | 45 | 32 |
ALE values for Study 2 (noxious heat). ALE values refer to the likelihood of obtaining activation evoked by noxious heat stimuli in a given voxel of the standard template. Coordinates are in Talairach space [Talairach and Tournoux 1988]. Cluster #: The clusters are ranked according to their size in millimeters cubed (mm3). Abbreviations: BA, Brodmann's Area; x, medial‐lateral; y, anterior posterior; z, superior‐inferior; SI, primary somatosensory cortex; IPL, inferior parietal lobule; SII, secondary somatosensory cortex; MI, primary motor cortex.