Table XVII.

Spatial location and extent of ALE values for study 3 (noxious heat vs. baseline minus noxious heat vs. warm)

Side	Region	BA	x	y	z	ALE value	P value	Cluster #	Volume (mm3)
Left	Cingulate gyrus	32	−2	10	40	0.039	<0.00001	1	2168
Left	Cingulate gyrus	24	−6	14	30	0.029	<0.00001
Left	Cingulate gyrus	32	−8	24	30	0.013	0.002
Right	SII	43	50	−18	16	0.020	<0.00001	2	1040
Right	SII	40	60	−30	26	0.015	0.0004
Right	SII	42	56	−12	12	0.014	0.0008
Right	Putamen		30	2	6	0.027	<0.00001	3	944
Left	Thalamus		−16	−20	12	0.035	<0.00001	4	688
Right	Inferior frontal gyrus	44	54	6	10	0.026	<0.00001	5	624
Right	Cerebellum		0	−66	−16	0.023	<0.00001	6	536
Right	Cerebellum		20	−66	−24	0.020	0.0004	7	488
Right	Cerebellum		30	−76	−28	0.014	0.0008
Left	Mid‐insula		−40	0	8	0.019	<0.00001	8	448
Left	Anterior insula		−38	12	12	0.014	0.002
Right	Medial frontal gyrus	6	6	−6	62	0.019	0.0006	9	320
Right	SI/PPC		22	−42	66	0.021	0.0002	10	240
Left	MI	4	−32	−22	50	0.020	0.0002	11	224
Right	SI	3	30	−30	62	0.019	0.0004	12	216
Left	Putamen		−22	0	−4	0.021	0.0002	13	192
Left	Posterior insula		−44	−26	16	0.018	<0.00001	14	168
Right	Thalamus		14	−20	4	0.018	0.0002	15	160
Right	Inferior frontal gyrus	6	46	0	30	0.017	0.0004	16	152
Right	Cerebellum		38	−54	−36	0.016	0.0002	17	144
Left	Superior frontal gyrus	6	−10	−8	72	0.021	0.0002	18	120
Right	Posterior insula/claustrum		30	−8	18	0.016	0.0002	19	112

Study 3: ALE values refer to the likelihood of obtaining activation evoked by noxious heat stimuli in comparison to resting baseline minus ALE values obtained for noxious heat in comparison to innocuous warm stimuli. Coordinates are in Talairach space [Talairach and Tournoux 1988]. Cluster #: The clusters are ranked according to their size in millimeters cubed (mm³). Abbreviations: BA, Brodmann Area; x, medial‐lateral; y, anterior posterior; z, superior‐inferior; SI, primary somatosensory cortex; PPC, posterior parietal cortex; SII, secondary somatosensory cortex; MI, primary motor cortex.