Table XVIII.

Spatial location and extent of ALE values for study 3 (noxious heat vs. warm minus noxious heat vs. baseline)

Side	Region	BA	x	y	z	ALE value	P values	Cluster #	Volume (mm3)
Right	Cingulate Gyrus	24	6	20	24	0.048	<0.00001	1	976
Left	Cingulate Gyrus	23	−2	−22	32	0.029	<0.00001	2	600
Right	Anterior insula	13	38	8	−4	0.028	<0.00001	3	464
Right	Cerebellum		16	−58	−12	0.021	<0.00001	4	256
Right	Lentiform Nucleus		30	−14	8	0.018	0.0002	5	192
Left	Superior Temporal Gyrus	22	−50	−4	6	0.021	<0.00001	6	184
Right	Cingulate Gyrus	24	6	0	38	0.019	<0.00001	7	184
Left	Posterior insula	13	−38	−20	14	0.018	0.0004	8	152
Right	Mid‐insula	13	38	−2	12	0.016	0.001	9	136
Left	Cingulate Gyrus	24	−6	−6	40	0.018	0.0004	10	112
Right	Thalamus		4	−20	0	0.017	<0.00001	11	104
Left	Thalamus		−4	−14	8	0.015	0.001	12	104

Study 3: ALE values refer to the likelihood of obtaining activation evoked by noxious heat stimuli in comparison to innocuous warm stimuli subtracting ALE values obtained for noxious heat minus baseline. Coordinates are in Talairach space [Talairach and Tournoux 1988]. Cluster #: The clusters are ranked according to their size in millimeters cubed (mm³). Abbreviations: BA, Brodmann Area; x, medial‐lateral; y, anterior posterior; z, superior‐inferior.