Table XXIV.

Study 5 (noxious cutaneous stimuli)

Side	Region	BA	X	y	z	ALE value	P value	Cluster #	Volume (mm3)
Right	Thalamus		14	−18	4	0.027	<0.00001	1	4328
Left	Mid‐insula		−38	−2	4	0.032	<0.00001	2	4064
Right	Dorsal posterior insula		42	−18	14	0.035	<0.00001	3	1696
Left	Cingulate gyrus	24	−2	−4	44	0.027	<0.00001	4	1424
Right	Anterior insula		36	10	0	0.02	<0.00001	5	960
Right	IPL	40	48	−28	26	0.017	0.0002	6	648
Left	SII		−58	−20	22	0.021	<0.00001	7	472
Right	Mid‐insula/Mid‐Clastrum		36	−4	6	0.017	<0.00001	8	408
Left	Cingulate gyrus	24	0	16	26	0.017	<0.00001	10	384
Left	SII		−50	−30	16	0.024	<0.00001	11	368
Right	IPL	40	26	−36	54	0.022	<0.00001	12	368
Right	Precentral gyrus	44	48	2	8	0.017	0.004	13	320
Right	Posterior insula		44	−10	−4	0.02	<0.00001	14	304
Right	SI/PPC	7	28	−44	46	0.017	<0.00001	15	296
Right	IPL		52	−44	28	0.016	<0.00001	16	280
Right	Inferior frontal gyrus	47	40	28	2	0.016	0.0002	17	272
Left	Middle frontal gyrus	9	−24	32	30	0.013	0.0004	18	200

ALE values for Study 5. ALE values refer to the likelihood of obtaining activation evoked by noxious stimuli applied to muscles. Coordinates are in Talairach space [Talairach and Tournoux 1988]. Cluster #: The clusters are ranked according to their size in millimeters cubed (mm³). Abbreviations: BA, Brodmann Area; x, medial‐lateral; y, anterior posterior; z, superior‐inferior; IPL, inferior parietal lobule; SI, primary somatosensory cortex; SII, secondary somatosensory cortex; MI, primary motor cortex; PPC, posterior parietal cortex.