Table II.
Tower of London
R/L | Chemo group | Control group | Chemo < control group | Voxels | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
x | y | z | Z value | x | y | z | Z value | x | y | z | Z value | |||
Dorsolateral PFC | R | 48 | 27 | 36 | 4.17 | 30 | 36 | 42 | 5.62 | |||||
L | −48 | 18 | 45 | 4.36 | −48 | 27 | 33 | 5.06 | −48 | 6 | 39 | 3.25 | 16a | |
Ventrolateral PFC | R | 36 | 57 | 3 | 3.73 | 48 | 42 | −9 | 3.36 | |||||
L | −48 | 42 | −6 | 3.69 | −45 | 48 | −3 | 3.94 | ||||||
Premotor cortex | R | 30 | 21 | 45 | 4.13 | 27 | 21 | 45 | 5.01 | |||||
L | −27 | 21 | 48 | 4.02 | −27 | 21 | 48 | 5.30 | ||||||
L | −6 | 27 | 54 | 5.11 | −6 | 27 | 45 | 5.40 | ||||||
Precuneus | R | 9 | −72 | 54 | 5.71 | 9 | −72 | 54 | 6.73 | |||||
L | −9 | −60 | 57 | 4.92 | −9 | −60 | 57 | 5.72 | ||||||
PPC | R | 51 | −45 | 51 | 4.73 | 51 | −45 | 51 | 5.90 | 39 | −60 | 54 | 3.94 | 17 |
48 | −33 | 48 | 3.83 | 16 | ||||||||||
L | −45 | −51 | 45 | 4.70 | −33 | −75 | 48 | 5.63 | −30 | −60 | 57 | 3.43 | 10 | |
Dorsal striatum | R | 15 | −3 | 18 | 3.27 | 12 | −6 | 18 | 4.08 | |||||
L | −9 | −3 | 15 | 3.70 | −9 | 0 | 12 | 4.15 | ||||||
Inferior temporal G | R | 54 | −63 | −12 | 3.40 | 54 | −63 | −9 | 4.90 | |||||
L | −57 | −60 | −3 | 5.00 | −57 | −57 | −3 | 5.38 | ||||||
Occipital cortex | R | 15 | −54 | 21 | 4.02 | 15 | −60 | 21 | 4.11 | |||||
L | −15 | −63 | 24 | 3.31 | −15 | −60 | 21 | 3.45 |
BOLD activations (MNI coordinates) for the Active > Baseline contrast for breast cancer survivors after chemotherapy (Chemo Group), breast cancer survivors without chemotherapy (Control Group) and group interactions.
Abbreviations: R, right; L, left; PFC, prefrontal cortex; PPC, lateral posterior parietal cortex; G, gyrus. Main task effects for each group are reported at P < 0.05, FDR corrected. Group interactions are reported at P < 0.001 unless indicated otherwise.
ROI analysis at P < 0.005 uncorrected.