Table III.

Increased activation for patients in contrast to controls

		Coordinates
Anatomical region	Cluster extent	x	y	z	t‐Value	P‐value	No. of voxels
IC: Patients > controls
Left lingual gyrus	Fusiform gyrus, cerebellum, IOG, MOG	−36	−88	−20	4.46	0.000	166
Right cerebellum	Lingual gyrus, IOG, calcarine gyrus	12	−88	−20	3.29	0.001	77
Left temporal pole	IFG, MTG, STS, STG, precentral gyrus	−44	0	−20	3.21	0.001	159
Right IFG	Middle frontal gyrus	56	12	24	3.19	0.001	95
Left SMA	Medial and superior frontal gyrus	−8	8	56	3.05	0.001	22
Left cerebellum		−24	−40	−32	2.70	0.004	18
Right inferior frontal operculum	IFG, middle frontal gyrus, Rol.OP, insula	56	16	0	2.64	0.005	125
Left pallidum	Putamen, thalamus, caudatus, insula	−16	0	4	2.48	0.007	133
Right superior occipital gyrus	MOG, cuneus, precuneus, SPL	28	−68	20	2.44	0.008	57
Right hippocampus	Thalamus, putamen, parahippocampus	20	−20	−8	2.00	0.024	17
MP: Patients > controls
Left IOG	Cerebellum, fusiform gyrus, lingual gyrus, MOG	−48	−72	−20	3.34	0.001	76
Left IFG	Precentral gyrus	−56	12	16	2.81	0.003	24
Right IFG	Precentral gyrus, middle frontal gyrus, insula	56	12	20	2.73	0.004	65
Right IOG	Lingual gyrus, fusiform gyrus, calcarine gyrus	36	−88	−12	2.10	0.019	17

Coordinates (MNI), cluster extent and t‐values of the difference contrasts of iconic versus metaphoric gestures. Cluster level corrected at P < 0.05. MTG, middle temporal gyrus; IFG, inferior frontal gyrus; STG, superior temporal gyrus; IOG, inferior occipital gyrus; MOG, middle occipital gyrus; SFG, superior frontal gyrus; OFC, orbitofrontal cortex; SPL, superior parietal lobe; MFG, medial frontal gyrus; ITG, inferior temporal gyrus; Rol.OP, rolandic operculum; OL, occipital lobe; HC, hippocampus; SMA, supplemental motor area.