Table II.
SPM results of grey matter analysis
| P(FWE) | P(FWE/ cluster) | k | T | MNI | Atlas |
|---|---|---|---|---|---|
| IPS < controls | |||||
| 0.949 | 0.715 | 163 | 3.8 | 2 −48 72 | Right precuneus |
| 3.4 | −9 −60 72 | ||||
| IPS > controls | |||||
| No clusters | |||||
| MSA‐P < IPS | |||||
| 0.921 | 0.911 | 89 | 4 | 21 3 6 | Right putamen |
| MSA‐P > IPS | |||||
| 0.577 | 0.731 | 161 | 4.5 | 24 −42 69 | Right superior parietal lobule |
| 0.737 | 0.96 | 61 | 4.3 | 2 −73 49 | Right precuneus |
| 3.5 | 0 −69 37 | ||||
| 0.839 | 0.481 | 258 | 4.2 | −6 −49 67 | Left precuneus |
| 3.9 | −16 −46 64 | ||||
| 3.7 | −9 −58 69 | ||||
| PSP < IPS | |||||
| 0.047 | <0.001 | 5101 | 5.9 | 16 −39 −30 | (Right cerebellum) |
| 5.3 | 15 −61 −20 | ||||
| 5.3 | 22 −57 −17 | ||||
| 0.158 | <0.001 | 4216 | 5.4 | −28 −76 −36 | (Left cerebellum) |
| 5.3 | −20 −70 −23 | ||||
| 4.3 | −42 −78 −33 | ||||
| 0.826 | 0.84 | 118 | 4.3 | 14 −91 37 | Right occiptal pole |
| 0.895 | 0.948 | 71 | 4.2 | 54 5 21 | right precentral gyrus |
| 0.984 | 0.953 | 68 | 3.9 | 16 −46 −45 | (Right cerebellum) |
| PSP > IPS | |||||
| 0.498 | 0.923 | 84 | 4.7 | −14 −57 72 | Left lateral occipital cortex, superior division |
| 0.971 | 0.516 | 229 | 3.9 | 22 −45 69 | Right superior parietal lobule |
| MSA‐P > PSP | |||||
| No clusters | |||||
| MSA‐P < PSP | |||||
| No clusters | |||||
Clusters and local maxima (more than 8 mm apart) of the grey matter SPM analysis thresholded at P < 0.001 (uncorrected) are shown. Peak and cluster level corrected P values (FWE) are also displayed. Clusters surviving peak level FWE correction are printed in bold. Anatomical position was determined using FSL view atlas tools and the Harvard‐Oxford Cortical/Subcortical Structural Atlas; only the structure with the highest probability is reported. When no label was found in the atlas, the region was estimated visually and printed in brackets.
IPS, idiopathic Parkinson syndrome; MSA‐P, multiple systems atrophy (parkinsonian variant); PSP, progressive supranuclear palsy. k = size of the cluster in voxels.