Table II.
Brain regions showing seed‐based functional connectivity at a significance level of P < 0.05 (FDR corrected) with seed regions of interest (ROIs)
| Seed ROI | Brain region functionally connected with seed ROI | Talairach coordinates peak value (x, y, z) | t‐Score TD group | t‐Score HF‐ASD group | t‐Score TD vs. HF‐ASD | P value TD vs. HF‐ASD |
|---|---|---|---|---|---|---|
| aIC RH (Talairach coordinates: 36, 16, 2) | ||||||
| aIC LH | −40, 12, 5 | 18.43 | 11.68 | |||
| dACC RH | 5, 8, 44 | 13.96 | 6.36 | |||
| pMSFG RH | 6, 9, 52 | 12.74 | 6.80 | |||
| pIC RH | 36, −8, −4 | 9.76 | 5.26 | |||
| ACC RH | 4, 33, 26 | 10.66 | 6.03 | |||
| SFG RH | 34, 44, 28 | 14.06 | 7.85 | |||
| PreCG RH | 39, −5, 48 | 8.74 | 5.57 | |||
| IFG RH | 38, 2, 30 | 9.41 | NS | |||
| Amygd RH | 29, −6, −22 | 3.43 | NS | 4.35 | 0.0009 | |
| aMCC LH | −13, 2, 40 | 10.82 | 3.30 | |||
| pMCC RH | 4, −24, 38 | 8.25 | NS | |||
| SFG LH | −32, 49, 29 | 7.23 | 5.48 | |||
| OFC RH | 23, 49, 3 | 6.87 | 3.69 | |||
| IPS RH | 41, −52, 47 | 4.78 | NS | |||
| Thal RH | 7, −16, 9 | 7.32 | NS | |||
| aIC LH (Talairach coordinates: −34, 14, 2) | ||||||
| aIC RH | 36, 24, 5 | 15.24 | 10.06 | |||
| dACC RH | 7, 25, 34 | 11.75 | 9.95 | |||
| dMSFG RH | 4, 18, 50 | 12.63 | 5.59 | |||
| aMCC RH | 2, 7, 44 | 11.40 | 6.44 | |||
| aMCC LH | −3, 13, 41 | 11.30 | 6.06 | |||
| SFG RH | 32, 45, 25 | 10.62 | 4.66 | |||
| SFG LH | −33, 51, 25 | 9.36 | 9.38 | |||
| vPreCG LH | −55, 0, 20 | 7.35 | 3.54 | |||
| mIC LH | −42, −12,11 | 6.64 | 4.68 | |||
| OFC LH | −30, 48, −1 | 9.25 | NS | |||
| Thal LH | −9, −12, 2 | 7.15 | 3.57 | |||
| pMCC RH | 9, −25, 38 | 6.13 | 6.26 | |||
| vPreCG RH | 37, 2, 29 | 5.89 | 8.30 | |||
| IFG RH | 35, 11, 28 | 5.81 | 5.64 | |||
| DLPFC LH | −43, 11, 33 | 6.22 | NS | |||
| pIC LH | −38, −26, 14 | 4.92 | NS | |||
| pIC LH (Talairach coordinates: −38, −12, 7) | ||||||
| mIC LH | 43, −2, 12 | 14.22 | 8.70 | |||
| SII LH | −46, −27, 25 | 16.18 | 4.33 | |||
| MCC LH | −10, −6, 42 | 13.00 | 5.20 | |||
| MCC RH | 6, −7, 49 | 14.29 | 5.63 | |||
| dPostCG LH | −46, −28, 45 | 6.23 | NS | 3.62 | 0.002 | |
| vPostCG LH | −46, −26, 24 | 15.55 | 4.33 | 3.44 | 0.002 | |
| vPostCG RH | 63, −14, 29 | 11.11 | 3.47 | |||
| dPostCG LH | −38, −21, 51 | 9.71 | NS | 3.38 | 0.003 | |
| dPreCG RH | 51, −15, 51 | 11.53 | 4.62 | |||
| SII RH | 53, −21, 19 | 11.98 | 5.80 | 3.48 | 0.002 | |
| Thal LH | −10, −20, 1 | 6.59 | NS | |||
| Thal RH | 11, −18, 1 | 7.34 | 3.99 | |||
| SPC LH | −38, −43, 61 | 6.90 | NS | |||
| pIC RH (Talairach coordinates: 38, −10, 7) | ||||||
| pIC LH | −45, −23, 16 | 13.88 | 6.61 | |||
| pIC RH | 40, −18, 14 | 14.74 | 10.44 | |||
| mIC LH | −46, −9, 6 | 14.09 | 12.34 | |||
| vPostCG RH | 54, −14, 37 | 9.79 | 3.72 | |||
| vPostCG RH | 50, −19, 25 | 9.68 | 3.61 | |||
| vPostCG RH | 63, −6, 24 | 9.63 | 5.27 | |||
| vPostCG LH | −54, 0, 28 | 8.90 | 3.69 | 3.30 | 0.01 | |
| MCC RH | 3, −8, 39 | 7.54 | 5.13 | |||
| MCC RH | 6, 4, 39 | 5.71 | 3.66 | |||
| Thal RH | 17, −26, 4 | 6.31 | 3.22 | |||
| MCC LH | −8, −4, 42 | 5.15 | 5.13 | |||
| dPostCG RH | 41, −20, 57 | 4.48 | NS | |||
| mIC LH | −38, −1, 1 | 11.03 | 6.88 | |||
LH, left hemisphere; RH, right hemisphere; aIC, anterior insular cortex; mIC, midinsular cortex; pIC, posterior insular cortex; (a/p)MCC, (anterior/posterior) midcingulate cortex; (d)ACC, (dorsal) anterior cingulate gyrus; (v/d)PreCG, (ventral/dorsal) precentral gyrus; Amygd, amygdala; Thal, thalamus; SFG, superior frontal gyrus; IPS, intraparietal sulcus; MSFG, medial superior frontal gyrus; IFG, inferior frontal gyrus; OFC, orbitofrontal cortex; DLPFC, dorsolateral prefrontal cortex; (v/d)PostCG, (ventral/dorsal) postcentral gyrus; SII, secondary somatosensory cortex.