Table IV.
Regions exhibiting differences in brain activation (intrinsic alertness [IA] condition) and functional connectivity (alertness‐related network 1) in preHDnear compared to controls and preHDfar individuals
| Controls > preHDnear | No. of voxels | preHDfar > preHnear | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Anatomical region | x | y | z | Z | Anatomical region | x | y | z | Z | No. of voxels | ||
| IA condition | Right putamen | 20 | 12 | −4 | 3.68 | 131 | Right putamen | 28 | 10 | −6 | 3.91 | 294 |
| Right middle frontal gyrus (BA 9) | 40 | 34 | 28 | 3.66 | 75 | Right lingual gyrus (BA 18) | 18 | −90 | −4 | 4.04 | 112 | |
| Left medial frontal gyrus (BA 6) | −4 | −6 | 56 | 3.27 | 79 | |||||||
| Alertness‐related network 1 | Left precentral gyrus | −18 | −14 | 68 | 4.50 | 633 | Left precentral gyrus | −16 | −14 | 68 | 4.26 | 445 |
| Left medial frontal gyrus (BA 6) | −4 | −6 | 52 | 4.49 | Left medial frontal gyrus (BA 6) | −4 | −6 | 52 | 3.85 | |||
Results from second level between‐group analyses (ANOVA model, P < 0.001, uncorrected at the voxel‐level, spatial extent threshold of at least 50 contiguous voxel).