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Experimental design of one fMRI scanning session. Subjects were submitted to three conditions (natural image, imagery with closed eyes, and scrambled image) in a block design (21 sec per condition; 3 conditions per block, 7 blocks per session). Each subject performed two fMRI sessions. In the first session, subjects were scanned before Ayahuasca intake. Immediately after the first scan, subjects drank Ayahuasca. The second fMRI session began 40 min after intake.
