Figure 4.

Relationship between prefrontal lobe network functional connectivity and fasting insulin levels (log_e‐scaled) and insulin sensitivity index (log_e‐scaled) in lean and obese subjects. Color map represents significant (P <0.05, FWE) voxels of insulin associated connectivity. Color bar represents T‐values. The left scatter plot shows a significant positive correlation between the left orbitofrontal cortex (x = −30, y = 45, z = −12) and fasting insulin, adjusted for BMI. The right scatter plot shows a significant negative correlation between left orbitofrontal cortex and insulin sensitivity index, adjusted for BMI.