Table V.

Functional connectivity in the left M1 in the resting state in normal subjects and patients with Parkinson's disease

Brain region	Coordinates			Brodmann area	t value	Cluster size	r Mean	r SD
	x	y	z
Normal subjects
L Postcentral Gyrus	−46	−25	44	2	4.58	567	0.172	0.189
L M1	−28	−18	50	4	4.81	1809	0.159	0.101
R M1	38	−16	48	4	4.76	611	0.129	0.175
SMA proper	1	−19	53	6	5.43	540	0.186	0.177
R Postcentral Gyrus	38	−25	45	40	4.51	327	0.085	0.154
Patients
L Postcentral Gyrus	−42	−26	52	3	6.26	2108	0.138	0.230
L M1	−40	−19	41	4	6.60	9153	0.337	0.218
R M1	16	−25	56	4	4.42	459	0.087	0.142
SMA proper	4	−1	48	6	6.08	2538	0.133	0.159
L Paracentral Lobule	−10	−30	59	6	4.50	1107	0.098	0.191
R Postcentral Gyrus	40	−31	53	40	4.40	296	0.079	0.208
R Inferior Frontal Gyrus	58	4	20	44	6.23	621	0.092	0.141
R Superior Parietal Lobule	31	−70	44	7	−5.18	459	−0.046	0.180
R Medial Frontal Gyrus	1	31	32	9	−5.10	756	−0.084	0.100
R Middle Frontal Gyrus	43	28	32	9	−7.78	2214	−0.059	0.128
R Middle Temporal Gyrus	52	−61	23	39	−4.35	567	−0.095	0.162
L Inferior Frontal Gyrus	−43	43	9	46	−4.80	729	−0.157	0.172

List of the brain regions showing a significant connectivity with the left M1 in normal subjects and patients with PD (one sample t test, P < 0.05, FWE corrected). The coordinates are given as stereotaxic coordinates referring to the atlas of Talairach and Tournoux. Positive t value means positive connectivity between the brain regions and M1; Negative t value means negative connectivity between the brain regions and M1; L, left; R, right; M1, primary motor cortex; SD, standard deviation; SMA, supplementary motor area.