Table II.
Interaction and between‐group contrasts in the classical analysis on the differential contrasts from extinction to recall of extinction
| Cluster | Voxel | |||||
|---|---|---|---|---|---|---|
| P corr | k | F peak | X | Y | Z | |
| Average effect of condition (effect of time) | ||||||
| Insula and putamen (R) | 0.003 | 96 | 29.67 | 34 | −2 | 14 |
| Insula and putamen (L) | 0.018 | 76 | 23.96 | −32 | 2 | 0 |
| Cerebellum crus I and 6 (R) | 0.086 | 27 | 20.47 | 38 | −54 | −38 |
| Main effect of group (group × time interaction) | ||||||
| Inferior temporal and fusiform gyrus (L) | 0.070 | 22 | 29.70 | −42 | −12 | −36 |
| Post‐hoc test at recall of extinction: control > REMD (CSE) | ||||||
| Middle cingulate cortex (L,R) | 0.013 | 134 | t: 4.38 | 6 | 8 | 28 |
P corr stands for nonstationary, whole brain corrected cluster P‐values, k for the cluster size, F peak for the F‐value of the peak‐voxel, t for t‐value, [x, y, and z] coordinates are in MNI‐space. Note that there were no significant clusters of activation in the group × stimulus interaction. The cluster in the middle cingulate cortex at recall of extinction was not significant when controlled for the three covariates sleep restriction, S2 amount and S4 amount, due to trend‐wise correlations of this cluster with sleep restriction (P corr = 0.076, k = 56, t peak = 4.63) and with S2 amount (P corr = 0.057, k = 85, t peak = 6.26). A brainstem cluster at [4‐34‐28] was noted in the group × time interaction (P corr = 0.420, k = 14, F peak = 24.44).