Table II.

Regions showing ALFF differences among the AD, MCI patients, and healthy controls (without and with GM correction)

Brain regions	BA	Vol (mm3)	MNI coordinates (mm)			Maximum Z
			x	y	z
Without GM correction
PCC/PCu	23/31/7	8,883	12	−63	33	7.92
Left PHG/Hip/STG	35/28/22	7,398	−33	−21	−24	7.54
Left LN	N/A	1,701	−21	6	−6	6.88
Left FG/ITG	37/36/20	4,104	−27	−60	6	6.86
Right PHG/Hip	35/36	2,538	36	−12	−27	6.75
Left IPL	40	1,620	−33	−75	30	6.54
Left PCL	5	4,779	−9	−30	54	6.24
Left MFG/MPFC/OFG	10/11	2,133	−18	42	−12	5.87
Left SFG/MFG	10/11	1,890	−27	45	18	5.80
SFG/SMA	5/6	3,591	3	3	69	5.65
Right ALC	N/A	1,890	6	−36	−6	5.52
Left PoCG	40	1,944	−39	−42	51	5.51
Right IOG/ITG	19/37	2,160	39	−69	−9	4.99
With GM correction
Left PHG/Hip/STG	35/28/22	2,484	−33	−21	−24	7.51
Left FG/ITG	37/36/20	3,537	−27	−60	6	6.83
Left PCL	5	3,267	−9	−30	54	6.41
Right IOG/ITG	19/37	1,998	39	−66	−12	6.34
Left LN	N/A	1,296	−21	6	−6	6.12
Left PoCG	40	864	−33	−27	42	6.03
Right ALC	N/A	1,620	9	−42	−12	6.01
Left MFG/MPFC/OFG	10/11	1,566	−18	42	−12	5.97
PCC/PCua	23/31/7	837	−3	−51	30	5.78
SFG/SMA	5/6	1,593	15	9	51	5.57
Left SFG/MFG	10/11	1,512	−27	39	15	5.18

x, y, z, coordinates of primary peak locations in the MNI space; Z, statistical value of peak voxel showing ALFF differences among the three groups. ALC, anterior lobe of cerebellum; BA, Brodmann's area; FG, fusiform gyrus; Hip, hippocampus; IOG, inferior occipital gyrus; IPL, inferior parietal lobule; ITG, inferior temporal gyrus; LN, lentiform nucleus; MFG, middle frontal gyrus; MPFC, medial prefrontal cortex; N/A, not applicable; OFG, orbitofrontal gryus; PCC/PCu, posterior cingulate cortex/precuneus; PCL, paracentral lobule; PHG, parahippocampa gyrus; PoCG, postcentral gyrus; SFG, superior frontal gyrus; SMA, supplementary motor area; STG, superior temporal gyrus. P < 0.05, corrected for multiple comparisons.

^aThe PCC survived the height but not the extent threshold.