Table VI.

Regions showing significant correlations between ALFF and MMSE for the AD and MCI patients (without and with GM correction)

Brain regions	BA	Vol (mm3)	MNI coordinates (mm)			Maximum Z
			x	y	z
Without GM correction
Left PHG/ITG	20	1,917	−36	−15	−42	−4.84
Right PHG	20	270	36	−12	−27	−4.19
Right SFG	8	1,161	21	12	57	−3.26
Left PCL	5	702	−12	−33	51	3.48
Left MPFC/OFG	11	918	−9	39	−18	3.19
Right PCua	31	351	15	−66	24	2.58
Left PCCa	29	189	−6	−48	15	2.52
With GM correction
Left PHG/ITG	20	1,134	−36	−15	−42	−4.76
Left PHG/ITG	20/19	351	−33	−21	−24	−3.35
Right PHG	20	135	27	−15	−24	−3.21
Right SFG	8	1,026	21	12	57	−3.14
Left MPFC/OFG	11	702	−9	39	−18	3.21
Left PCL	5	540	−6	−33	51	3.07
Right PCub	31	297	15	−66	24	2.54

x, y, z, coordinates of primary peak locations in the MNI space; Z, statistical value of peak voxel showing significant correlations between ALFF and MMSE score in the AD and MCI subjects. Negative Z values indicate negative correlations between ALFF and MMSE scores, vice versa. BA, Brodmann's area; ITG, inferior temporal gyrus; MPFC, medial prefrontal cortex; PCC, posterior cingulate cortex; PCL, paracentral lobule; PCu, precuneus; PHG, parahippocampa gyrus; SFG, superior frontal gyrus. P < 0.05, corrected for multiple comparisons.

^aTwo clusters in the PCC (243 mm³) and PCu (459 mm³) survived the height but not the extent threshold.

^bThe cluster in the PCu (378 mm³) survived the height but not the extent threshold.