Figure 2.

Down‐regulation of reward‐related striatal activation in highly impulsive subjects during the “desire‐reason dilemma.” Significant down‐regulation of activation in the right Nacc during the desire‐reason dilemma” in HI subjects (dilemma‐related deactivations are displayed on a coronal slice of the MNI template; see also Table II). The bar graph shows the mean parameter estimates for the reward signal in the right Nacc (in the comparison against implicit baseline) in the “desire context,” in which the conditioned (rewarding) stimulus was selected when it occurred as a nontarget, and during a “desire‐reason dilemma,” which required a rejection of the (same) conditioned stimulus in the “reason context.” Error bars depict the standard error of the mean. A significant down‐regulation of striatal activation during the dilemma could only be observed in the HI group. [Color figure can be viewed in the online issue, which is available at wileyonlinelibrary.com.]