Table III.
Brain regions showing load‐dependent brain activation differences between healthy control subjects and HD patients during the delay period
| WM load level | Anatomical region | x | y | z | Z |
|---|---|---|---|---|---|
| Load level 2 | Right cerebellum | 27 | −63 | −30 | 4.45 |
| Load level 3 | Left middle frontal gyrus (BA 9) | −30 | 33 | 36 | 4.46 |
| Left inferior frontal gyrus (BA 44) | −51 | 0 | 39 | 4.10 | |
| Right inferior parietal lobule (BA 40) | −51 | −45 | 51 | 3.92 | |
| Left precuneus (BA 7) | −9 | −69 | 48 | 4.42 | |
| Right precuneus (BA 7) | 3 | −53 | 54 | 4.35 | |
| Left superior parietal gyrus (BA 7) | −27 | −50 | 48 | 4.40 | |
| Left putamen | −18 | 9 | −3 | 4.10 | |
| Right cerebellum | 30 | −63 | −33 | 5.42 | |
| Brainstem | 12 | −33 | −48 | 3.82 |
Results of the between‐group ANCOVA, P < 0.001 (uncorrected at the voxel level, P < 0.05 corrected for spatial extent).
x, y, and z are Talairach coordinates of the most significant center of activation within an activated cluster; Z = Z‐value; BA = Brodmann Area.