Table III.
Mean diffusivity of region‐of‐interest in CS, MCI and AD
MD (10−9 m2/s) | CS (n = 16) | MCI (n = 13) | AD (n = 11) | MCI/AD (n = 24) |
---|---|---|---|---|
PVWM | ||||
Anterior right | 0.87 (0.09) | 0.92 (0.16) | 0.93 (0.14) | 0.93 (0.15) |
Anterior left | 0.79 (0.09) | 0.90 (0.18)* | 0.90 (0.16)* | 0.90 (0.16)* |
Posterior right | 0.87 (0.09) | 0.95 (0.17) | 0.92 (0.18) | 0.93 (0.17) |
Posterior left | 0.89 (0.13) | 0.95 (0.22) | 0.92 (0.12) | 0.94 (0.18) |
SCWM | ||||
Anterior right | 0.76 (0.03) | 0.76 (0.06) | 0.80 (0.14) | 0.78 (0.10) |
Anterior left | 0.69 (0.06) | 0.72 (0.07) | 0.72 (0.10) | 0.72 (0.08) |
Posterior right | 0.81 (0.05) | 0.78 (0.08) | 0.78 (0.07) | 0.78 (0.05) |
Posterior left | 0.81 (0.06) | 0.78 (0.08) | 0.80 (0.06) | 0.79 (0.07) |
Temporal right | 0.85 (0.07) | 0.89 (0.08) | 0.87 (0.06) | 0.88 (0.07) |
Temporal left | 0.85 (0.05) | 0.86 (0.63) | 0.84 (0.08) | 0.85 (0.07) |
Corpus callosum | ||||
Genu | 0.81 (0.34) | 1.00 (0.25)* | 1.01 (0.22)* | 1.01 (0.23)* |
Splenium | 0.87 (0.06) | 0.91 (0.11) | 0.89 (0.09) | 0.91 (0.10) |
MD, mean diffusivity (standard deviation); PVWM, periventricular white matter; SCWM, subcortical white matter; CS, control subjects; MCI, mild cognitive impairment; AD, Alzheimer's disease; *P < 0.05 analysis of variance with post hoc between AD and/or MCI and CS.