Table IV.
Fraction anisotropy of region‐of‐interest in CS, MCI and AD
| FA | CS (n = 16) | MCI (n = 13) | AD (n = 11) | MCI/AD (n = 24) |
|---|---|---|---|---|
| PVWM | ||||
| Anterior right | 0.38 (0.08) | 0.34 (0.10) | 0.30 (0.05)* | 0.32 (0.08)* |
| Anterior left | 0.39 (0.05) | 0.34 (0.10) | 0.30 (0.05)** | 0.32 (0.09)** |
| Posterior right | 0.47 (0.08) | 0.45 (0.10) | 0.44 (0.09) | 0.45 (0.09) |
| Posterior left | 0.47 (0.09) | 0.44 (0.11) | 0.43 (0.08) | 0.44 (0.10) |
| SCWM | ||||
| Anterior right | 0.45 (0.05) | 0.44 (0.04) | 0.42 (0.06) | 0.43 (0.05) |
| Anterior left | 0.45 (0.05) | 0.47 (0.05) | 0.47 (0.06) | 0.47 (0.05) |
| Posterior right | 0.43 (0.06) | 0.44 (0.05) | 0.42 (0.06) | 0.43 (0.05) |
| Posterior left | 0.44 (0.04) | 0.46 (0.06) | 0.41 (0.05)† | 0.44 (0.06) |
| Temporal right | 0.46 (0.06) | 0.43 (0.07) | 0.44 (0.04) | 0.44 (0.06) |
| Temporal left | 0.49 (0.06) | 0.45 (0.07) | 0.48 (0.05) | 0.47 (0.06) |
| Corpus callosum | ||||
| Genu | 0.78 (0.07) | 0.74 (0.09) | 0.70 (0.09)* | 0.72 (0.09)* |
| Splenium | 0.75 (0.06) | 0.75 (0.05) | 0.75 (0.05) | 0.75 (0.05) |
FA, fraction anisotropy (standard deviation); PVWM, periventricular white matter; SCWM, subcortical white matter; CS, control subjects; MCI, mild cognitive impairment; AD, Alzheimer's disease; *P < 0.05; **P < 0.01, analysis of variance with post hoc between AD and/or MCI and CS; †P < 0.05, analysis of variance with post hoc between AD and MCI.